CRISPR-children: the next giant leap for mankind

In late November, the MIT Technology Review told us an amazing story: the story of the birth of the first children who went through the edit genes being embryos. Then it became known that a miracle happened in a small Chinese hospital, in which seven couples, including HIV-positive men who gave the egg and the seed of the doctor Heh Stankoi and his colleagues from the southern research Institute of Shenzhen for editing, applying CRISPR-Cas9. Their goal was the removal of the molecular “door” that allows the AIDS virus to penetrate the T-cells, resulting in two children — twin girls — were immune to HIV.

Such a breakthrough would be cause for worldwide celebration. But instead, the response in the media and the scientific community suggests that humanity was literally frozen in indecision in front of their next big leap.

Genetic editing of children: Yes or no?

Accurate, consistent, and rational “debugging” of the source code of the person should be one of the greatest defining moments of our collective history. The lack of transparency, questionable use, shady ethics and poor explanation of Dr. Heh it difficult to predict what will happen next.

The complete lack of public data in this story is amazing. Transparency is considered — or was considered — one of the main defining characteristics of science. The words of Carl Sagan, “extraordinary claims require incredible evidence”. Dr. Hye said that his team had acted within the ethics of using data from DNA sequencing, that it was from these and other embryos. But where is the data? Where was the independent oversight on these data analyses, before the embryos are introduced into the mother?

Victory over AIDS would be nice for a first application of CRISPR-Cas9 to the germ line of a person — but are we missing an important opportunity? As many have noted, we already know how to deal with HIV / AIDS (condoms, antiretroviral treatment and education have proven effective). Clinical trials have already set us on a course of AIDS treatment ex vivo. These baby girls, in particular, the Protocol of purification, through which passed the sperm of the father, minimized the chances of transmission of the disease at conception.

For one giant leap for mankind in the future as rationally edited, we could fight genetic diseases that are hard to reach in the body and still have horrible predictions. Cystic fibrosis (affecting multiple systems of the body) and Alzheimer’s (which for decades did not respond to treatment) come to mind immediately.

Dr. Hye strongly defended the ethics of his work, but many scientists and non-scientists disagree with him. It is unclear whether parents have been informed properly before you sign the paper, whether there were any omissions. In addition, one of the twins could have only partial protection in some cells (this phenomenon is known as mosaicism) from CRISPR. The team of Dr. Hyo could know about this mosaicism before he placed the child in the womb. If the girl would not be immune to HIV, then what was the point of the experiment?

Although these technical and ethical concerns are deeply concerned about us, far more thrilling in this story is the emerging picture around one of, if not the most important steps of mankind. Dr. Hye argues that this mixed picture was the result of an unexpected leakage. The coming days will show, if acted his team scientifically, ethically and responsibly.

Most excited about what we’re talking about two girls. Two children. Two people.

To protect children from exploitation is extremely important. Unfortunately, now, when people talk about this story, they talk about “embryos”. Not about names and not about the person. No reports of “mother and children in order”. No ultrasound with a happy mother. Instead, we read of must have been these children to be born or not.

Whether the child conceived in the IVF process is less human than a child conceived in a traditional way? This talk was supposed to stop by today. Currently, in many places of the world, no one even blinks when there is an ECHO. In 50 years our descendants may not be able to imagine how we could reproduce in such an uncomfortable way.

In short: children with the edited genome the same people, as we all do.

You think this hitch before jumping to the progress of our species? Or we will take the opportunity to change our species into something more strong, kind, sturdy? The decisions we make today will shape our future.

Which option will you choose? Tell us in our chat in Telegram.

0 Comments on “CRISPR-children: the next giant leap for mankind”

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    In December of 2017, Donald Trump made history by recognizing Jerusalem as the capital of Israel Why is this big news? Because by this the Jewish people of Israel are now able to press forward in bringing about the Third Temple prophesied in the Bible

    Jewish Rabbis have publicly announced that their Messiah will be revealed in the coming years who will be a leader and spiritual guide to all nations, gathering all igions under the worship of one God

    Biblical prophecy tells us that this Jewish Messiah who will take the stage will be the antichrist who opposes and exalts himself above all that is called God or that is worshiped, so that he sits as God in the temple of God, showing himself that he is God (2 Thessalonians 2:4) For a time he will bring about a false peace, but Therefore when you see the ‘abomination of desolation,’ spoken of by Daniel the prophet, standing in the holy place (Matthew 24:15) then there will be great tribulation, such as has not been since the beginning of the world until this time, no, nor ever shall be (Matthew 24:21)

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    He causes all, both small and great, rich and poor, free and slave, to receive a mark on their right hand or on their foreheads, and that no one may buy or sell except one who has the mark or the name of the beast, or the number of his name

    Here is wisdom Let him who has understanding calculate the number of the beast, for it is the number of a man: His number is 666

    Referring to the last days, this could only be speaking of a cashless society, which we have yet to see, but are heading towards Otherwise, we could still buy or sell without the mark amongst others if physical money was still currency This Mark couldn’t be spiritual because the word references two different physical locations If it was spiritual it would just say in the forehead RFID microchip implant technology will be the future of a one world cashless society containing digital currency It will be implanted in the right-hand or the forehead, and we cannot buy or sell without it Revelation 13:11-18 tells us that a false prophet will arise on the world scene doing miracles before men, deceiving them to receive this Mark Do not be deceived! We must grow strong in Jesus AT ALL COSTS, DO NOT TAKE IT!

    Then a third angel followed them, saying with a loud voice, “If anyone worships the beast and his image, and receives his mark on his forehead or on his hand, he himself shall also drink of the wine of the wrath of God, which is poured out full strength into the cup of His indignation He shall be tormented with fire and brimstone in the presence of the holy angels and in the presence of the Lamb And the smoke of their torment ascends forever and ever; and they have no rest day or night, who worship the beast and his image, and whoever receives the mark of his name” (Revelation 14:9-11)

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    Jesus came to free us from the bondage of sin The everlasting fire was prepared for the devil and his angels due to disobedience to God’s law If we do the same, what makes us any different than the devil? Jesus says unless we repent, we shall perish For sin is the transgression of the law We must walk in the Spirit so we may not fulfill the lusts of the flesh, being hatred, fornication, drunkenness and the like Whoever practices such things will not inherit the kingdom (Galatians 5:16-26) If we sin, we may come before Jesus to ask for forgiveness (1 John 2:1-2) Evil thoughts are not sins, but rather temptations It is not until these thoughts conceive and give birth by our own desires that they become sin (James 1:12-15) When we sin, we become in the likeness of the devil’s image, for he who sins is of the devil (1 John 3:8); but if we obey Jesus, in the image of God For without holiness, we shall not see the Lord (Hebrews 12:14)

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