Most people find it extremely difficult to Wake up in the morning, and it has nothing to do with their laziness and poor discipline. The fact that even in the absence of important cases and depending on the smartphone, they are unable to go to bed before midnight, but they need to sleep like any healthy person. In 2017, it has been proven that this is due to a genetic error where the body of some people can not fit in the required 24 hours — recently it became known, from-for what all this happens.
The first genetic mutation was identified in 46-year-old woman, whose circadian rhythm was set to a fairly long 25 hours. The examination of the body, the researchers noticed a small mutation in the gene CRY1, which is responsible for the receiving cells to ultraviolet light. While for digestion, cell repair, and other processes people have 24 hours to her all this required much more time due to the backlog in its rhythms 2-2.5 hours.
New research has shown what exactly is going on this lag. The fact that the circadian rhythm each day begins with the accumulation of proteins, called activators. During the day they produce their own inhibitors, which suppress the physico-chemical processes and thereby interfere with work even there most of the activators. When the number of cease inhibitors, activators again begin to accumulate, triggering the circadian rhythm of a new day. This process occurs throughout a person’s life.
A mutation in the gene CRY1 leads to a long lock-UPS and, consequently, to delays the internal clock. As a result, people with this mutation are not able to sleep “normal” for other people’s time, and as a result can not get up early and feels tired throughout the day.
Fortunately, researchers believe that to improve your you can use external signals such as light. For example, the syndrome of delayed sleep phase patients are recommended when you Wake up turn on bright light power 2500-10000 Lux, and before going to bed to avoid any light, especially coming from the screens of smartphones and computers to blue spectrum.
Good sleep hygiene can make a slow internal clock to operate in the normal mode, people just need to work harder on it. It is not excluded that on the basis of this knowledge, new medicines are developed.
Alina Patke, a researcher from the Rockefeller University
Of course, in severe cases, does not help even a medical therapy. There is only one solution — to adjust the life of the individual circadian rhythm.
Is it difficult to get up in the morning? What is the reason? Their answers to share in the comments or in our Telegram chat.