According to the world health organization, each year die from severe burns to more than 180 000 people. Fortunately, the surgeons unable to save victims of fires and other accidents from death by transplanting skin from another part of the body, but this process lasts a long time. During the preparation of the patient’s skin burn wound usually override the donor’s skin, but it is always in short supply and is extremely expensive. In an alternative donor tissue doctors from the us state of Massachusetts decided to use pig skin. To their surprise, the operation was a success and the alien fabric perfectly acclimatized on the human body.
Many of us already school years it is known that in the body of the pig flow is almost the same physiological processes as humans. That is why kidney, liver, spleen and other organs of pig are often used for transplantation into the human body. However, scientists are still unable to establish a transplant of foreign skin into the body of the burnt man, because she may be rejected by the immune system due to the presence in pig skin so-called endogenous retroviruses.
The skin graft operation
These viruses can cause various infections, therefore, alien skin and can be rejected by the protective system of the human body. However, if the scientists removed a certain gene sequence, rejection can be avoided. In General, no editing of genes no pork organ cannot be transplanted into the human body. Based on this, the American scientists decided to change the genetic code of the sample pig tissue and try to temporarily sew it to the burn wound of a patient.
Before applying the alien tissue, the surgeons cleaned the wound man from dead skin. Then on the burned surface surgeons put a genetically modified pig’s flesh dimensions 5×5 cm. Next to the segment of pig skin was applied a sample of tissue from a donor person. Both patches were secured with surgical staples, and gauze bandages. Read more about the study can be read on the website Eurekalert.
How to heal severe burns?
Five days later, the surgeons checked the affected areas and found that is covered with pig and human tissues space visually almost indistinguishable. No side effects like irritation were noted and healing took place in normal mode. In addition to this, experts from Management on sanitary inspection behind quality of foodstuff and medicines USA (FDA), carefully checked the work of American researchers. They confirmed that the tissue samples no virus was detected, so the compatibility of pig and human skin is not surprising.
By the way, do you know why China started to grow a huge pig?
According to the surgeon Jeremy Goverman, who led the study, in the future, edit the genes may open new opportunities to treat people with severe burns. Soon he and his team intend to conduct an experiment with the participation of more volunteers. If all goes well, in the future the surgeons will begin to use non-human and swine donor skin and the deficit will be forgotten.
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Generally, this opening is very happy, because burns is a very common injury. Severe damage can be obtained even when wearing overalls with reflective tape. For example, a trauma recently received a 40-year-old man who walked around in uniforms in hot weather. More information about this event, read our special article.