Cancer is the second leading cause of death worldwide after cardiovascular diseases. Sometimes doctors can remove the primary tumor and people have hope for a full recovery. However, if tumors arise so-called metastasis and it starts to spread, the chances of a full recovery are much reduced. However, scientists from Belgium trying to find is not the first year looking for a way to stop the complications of cancer and a recent study found that the disease spreads, using as energy source the human body fat. So as it turns out, to stop the development of cancer with the help of funds from the obesity?
The results of the Belgian scientific work has been published in the journal Nature Communications. A group of scientists under the leadership of Olivier Feron continued their previous study and found that cancer cells accumulate fats in tiny bubbles, which was called the lipid droplet. Fats are used as energy source, so it is logical that saturated their cells spread much faster than the others.
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As fat contributes to the development of cancer?
According to scientists, the accumulation of fat in the cells and the aggressive behavior of cells is a protein of TGF-beta2, also known as the transforming growth factor beta. It is a kind of switch, which allows cancer cells to store energy, and on the other it forces them to use the received power for distribution.
The research compared all the above with how the climbers gather in the way of food and equipment. Their collected goods helps them to climb to great heights, despite the harsh weather conditions.
Thanks to the new discovery, scientists were able to develop a new plan to slow the development of cancer. In theory to stop the occurrence of metastases, researchers need to develop means for blocking production of the protein TGF-beta2. Also it would be nice if future drug slowed down the formation of fats and their transport throughout the body. Just before that they need to make sure that the protein TGF-beta2 is not involved in other important to human life processes. Also, people on medication which is essentially the remedy of obesity have to follow a particular diet.
It is possible that in the world there are already suitable for these purposes, the drugs. Scientist it is important to study their composition and to test empirically whether they can slow the development of cancer. Typically, such tests are first carried out on laboratory mice. For example, in 2018, scientists have implanted a tiny human brain in the body of the roof and looked what happened.
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Generally, to defeat cancer can turning cancer cells into the fat. According to the scientific journal Cancer Cell, in 2019, Swiss scientists led by Professor Gerhard Cristofori and thus were able to prevent complications of cancer. By the way, they conducted an experiment on mice with aggressive breast cancer. This cancer often occurs in women, so the opening can be considered very important for the scientific community.